09/30/2025
Trying to lose weight but constantly battling cravings? You’re not alone. The good news is you don’t have to give up the fight or rely on willpower alone.
This article dives into the best natural appetite suppressant supplements that are formulated to help you feel full, eat less, and even burn more calories. We’ll explore supplements with scientifically-backed ingredients that work and show you how to use them safely.
Plus, we’ll break down why PhenQ is our #1 best appetite suppressant and introduce some other great options.
This all-in-one formula tackles weight loss from multiple angles and is perfect for those who want to kick-start their journey but don’t know what to focus on. PhenQ reviews claim it can help with cravings, metabolism, and even energy levels, all in one bottle.
In her five-star review on Trustpilot, Michele stated, “I really like the product, but what impresses me the most is their customer service.” Lotte also praised the support team, saying, “My package was incomplete, but they have great customer service and compensation!” Another user liked that PhenQ helped reduce their cravings [1] [2] [3].
On a less positive note, Lisa said she tried both the day and night formulation but didn’t see any results. She concluded, “I am sad it didn’t work, but I’m happy that PhenQ refunded my money [4].”
>>Check the best prices for PhenQ
Stuck in a weight loss rut? This supplement might be your new best friend! PhenGold is perfect for jumpstarting your weight loss journey or breaking through a stubborn plateau. It offers several fat-burning benefits, so whether you battle cravings or crave a metabolism kick, PhenGold could be the key.
PhenGold’s unclaimed Trustpilot page has only a handful of reviews, which isn’t enough to get the complete picture. The official website is also a dead end for balanced reviews. For more detailed feedback, you should check forums like Quora or Reddit, where many users have discussed the supplement.
>>Check the best prices for PhenGold
Are you tired of fighting cravings but don’t have time for a dedicated weight loss program? Trimtone is the best appetite suppressant for women with busy lives. It only requires a single dosage and includes a simple but deliberate formula to help you feel fuller for longer and burn more calories on the go.
The official website includes mostly positive reviews, like Cynthia, who said the supplement supported her fasting routine and evening workouts. There’s also Beth, a mom who said, “Trimtone has been a great fit for my busy schedule [5].” But for more rounded testimonials, check Reddit or Quora.
>>Check the best prices for Trimtone
If you need a dietary supplement that supports your weight loss journey both day and night, Phen24’s dual formula fits the bill. The daytime supplement includes natural ingredients that may help curb cravings, while the nighttime formula is formulated to keep your metabolism running even as you sleep.
Day Formula
Night Formula
In her five-star review on Trustpilot, Helga noted she has lost weight steadily and feels more energized throughout the day since she started taking Phen24. But Michael complained about late delivery and poor customer service [6] [7].
>>Check the best prices for Phen24
Cravings got you down, but you want a natural and vegan solution? Zotrim includes three key plant extracts backed by science to suppress appetite and reduce the formation of fat cells. Plus, it’s vegan-friendly, making it an excellent choice for those with dietary restrictions.
A great place to find a variety of user feedback is on online forums like Reddit or Quora, as there was only a single positive review on the official website.
>>Check the best prices for Zotrim
Instant Knockout Cut is ideal for fighters and athletes looking to build lean muscle. However, it’s also great for anyone who wants to control cravings and monitor their body mass index.
In his Amazon review, Ikram said that while he was hesitant to call it a “miracle pill,” it had certainly worked for him. He reported that he had lost approximately 7 lbs in a month, and that the supplement suppressed his appetite and the caffeine helped him in the afternoon [8].
Meanwhile, Wendy gave the supplement only 1 star and said, “Didn’t do absolutely anything for me. And it was not cheap [9].”
>>Check the best prices for Instant Knockout Cut
Natural appetite suppressants are supplements that claim to help reduce hunger and food intake by influencing the body’s natural processes or appetite hormones. These products are usually derived from herbs, plants, or other natural sources with some scientific evidence of affecting appetite in humans or animals.
Thinking about trying natural appetite suppressants? These supplements might be a great tool for reducing weight gain and managing your overall health. Here’s why:
Because they are made from natural ingredients like herbs, fibers, and plant extracts, these supplements are typically gentler on your body. When used as directed, they have a much lower risk of causing the severe side effects sometimes associated with prescription diet pills. This makes them a safer option for long-term use for many people.
Beyond just helping you eat less, some natural appetite suppressants contain ingredients that have added health benefits. For example, glucomannan (the soluble fiber found in many of these supplements) can help slow down the absorption of sugar, which can lead to more stable blood sugar levels. This can also help maintain healthy cholesterol levels [10].
The main job of an appetite suppressant is to help you feel full, and many natural options do this by using ingredients that are rich in soluble fiber. When you take these with water, they expand in your stomach and make it easier to eat smaller portions at meals without feeling hungry or deprived.
You probably know the struggle of stress eating. The best appetite suppressants can help curb those cravings triggered by boredom, stress, or a bad day.
Some ingredients, like chromium, 5-HTP, and garcinia, help balance your mood and blood glucose levels, which can directly impact your appetite. As a result, you feel more satisfied and in control of your diet even when you are stressed or upset [11] [12] [13].
>>Check the best prices for PhenQ
When choosing the best appetite suppressant pills, consider the following factors:
Before you jump in, do your homework! Read online reviews and see what other people are saying about the company. Look for any awards or certifications from trusted organizations—that’s a good sign! You want to feel confident about the company you’re buying from.
Avoid products loaded with artificial colors, weird fillers, or mystery chemicals. These can mess with your body and might not even work. Instead, look for supplements with clear labels that list the dosage, strength, and clean ingredients.
Look for appetite suppressants with minimal side effects that are okay for long-term use. But remember, it’s always a good idea to chat with your doctor before you start taking any new supplements, especially if you have any health concerns or take medications.
Your healthcare provider can help you find the right fit and ensure it’s safe for you. Always follow the instructions on the label, and don’t take more than recommended.
Compare prices and see how much you get for your money. Look at the cost per serving, how many servings are in a bottle, and the quality of the ingredients. Don’t forget to check for discounts, coupons, or free shipping because every penny counts!
Prioritize dietary supplements with a good track record of helping folks shed pounds and maintain a healthy weight. Check customer reviews, before-and-after pics, and see what others are saying.
Ideally, you want something that can help you reach your goals for the long haul. Bonus points if the company offers a money-back guarantee or free trial. That way, you can see if it works for you risk-free!
Make sure you understand the return policy before you buy. How long do you have to send it back? Does it need to be unopened? What kind of proof do you need? And how will you get your money back? Also, watch out for any hidden fees like shipping costs or restocking charges.
Some popular ingredients usually included in natural OTC appetite suppressants are:
CLA is a type of healthy fat found in dairy products, beef, and lamb. Studies show it can increase the breakdown of fat and reduce how much fatty acid is stored in the body [14].
This tropical fruit contains hydroxy citric acid (HCA), which inhibits an enzyme that produces body fat. It may also increase serotonin levels, which could reduce appetite and improve mood [15].
It’s a type of fiber that comes from the root of the konjac plant. It can absorb water and form a gel-like substance in the stomach, which can make you feel full and delay stomach emptying [16].
An extract that comes from unroasted coffee beans, green coffee contains chlorogenic acid and caffeine. Chlorogenic acid may slow down the absorption of carbohydrates and fat in the gut, while caffeine may boost metabolism and energy expenditure [17].
The extract is made from the leaves of the Camellia sinensis plant, which include catechins and caffeine. Catechins are antioxidants that may increase fat burning and thermogenesis, while caffeine may stimulate the nervous system and reduce appetite [18].
This mineral is involved in the metabolism of carbohydrates, fats, and proteins. It may enhance the action of insulin, a hormone that regulates blood sugar and hunger signals [19].
As a spice that contains capsaicin, this compound gives peppers their heat. Capsaicin may increase the production of heat in the body, which can burn more calories and suppress appetite [20].
>>Check the best prices for PhenQ
Some of the most common prescription appetite suppressants are:
While natural appetite suppressants are generally considered safer than prescription weight loss drugs, they still carry risks. Some natural ingredients can have common side effects like upset stomach, headaches, or increased heart rate, especially if they contain stimulants.
It’s also possible for these supplements to interact with other medications you’re taking or worsen pre-existing health conditions like high blood pressure.
Here, we answer a few popular questions about the best over-the-counter appetite suppressant supplements.
Yes, over-the-counter appetite suppressants can be effective, but their results vary widely among individuals. They are not a magic solution, but can be a helpful tool to support weight loss when combined with a proper diet and regular physical activity. These supplements typically use natural ingredients to help you feel fuller and curb cravings.
Using an appetite suppressant is not inherently bad, but it depends on the type, your health, and how you use it. Talk to a doctor before starting one.
The strongest appetite suppressants for weight loss are prescription-only medications, such as phentermine, which are much more powerful than any natural supplement. Because of their potential side effects, they require a doctor’s supervision.
Based on our review, PhenQ is the best over-the-counter appetite suppressant over the counter. Like other OTC weight loss supplements, it relies on ingredients like soluble fiber, stimulants like caffeine, or herbal extracts to create a feeling of fullness or boost metabolism.
There is no over-the-counter pill that is a direct equivalent to phentermine. However, many dietary supplements are designed to mimic its appetite-suppressing qualities using natural ingredients. Well-known examples are PhenQ, PhenGold, and Trimtone.
We have carefully examined the market and selected the six best appetite suppressant supplements for hunger control. PhenQ is our top pick, but the other five supplements also passed our high standards.
While appetite suppressants can be a valuable tool in your weight loss journey, remember that these supplements are most effective when combined with a healthy diet and regular exercise.
And as always, consult a healthcare professional before starting any new supplement regimen, particularly if you have a medical condition or are taking other medications.
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